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  1. Sarris, J., Ravindran, A., Yatham, L. N., Marx, W., Rucklidge, J. J., McIntyre, R. S., … Berk, M. (2022). Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce. The World Journal of Biological Psychiatry, 23(6), 424–455.
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  2. https://pubmed.ncbi.nlm.nih.gov/33144709/ :
    Marx W, Lane M, Hockey M…, Firth J, et al. (2020). Diet and Depression: Exploring the Biological Mechanisms of Action. Molecular Psychiatry, 2021.
  3. https://www.bmj.com/content/369/bmj.m2382 :
    Firth J, Gangwisch JE, Borsini A, Wootton RE, Mayer EA. Food and mood: how do diet and nutrition affect mental wellbeing?. The BMJ ; 2020 Jun 29;369.
  4. https://link.springer.com/article/10.1007/s00394-019-02090-6 :
    van der Burg, K. P., Cribb, L., Firth, J., Karmacoska, D., Mischoulon, D., Byrne, G. J., … & Sarris, J. (2020). EPA and DHA as markers of nutraceutical treatment response in major depressive disorder. European journal of nutrition, 59, 2439-2447.
  5. https://onlinelibrary.wiley.com/doi/abs/10.1002/wps.20672 :
    Firth, J., Teasdale, S. B., Allott, K., Siskind, D., Marx, W., Cotter, J., … & Sarris, J. (2019). The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta‐review of meta‐analyses of randomized controlled trials. World Psychiatry, 18(3), 308-324.
  6. Guu TW, Mischoulon D, Sarris J, Hibbeln J, McNamara RK, Hamazaki K, Freeman MP, Maes M, Matsuoka YJ, Belmaker RH, Jacka F, Pariante C, Berk M, Marx W, Su KP. International Society for Nutritional Psychiatry Research Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major Depressive Disorder. Psychother Psychosom. 2019;88(5):263-273. doi: 10.1159/000502652. Epub 2019 Sep 3. PMID: 31480057.
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  7. https://www.tandfonline.com/doi/abs/10.1080/1028415X.2019.1625222 :
    Van Der Burg KP, Cribb L, Firth J, Karmacoska D, Sarris J. Nutrient and genetic biomarkers of nutraceutical treatment response in mood and psychotic disorders: a systematic review. Nutritional neuroscience. 2021 Apr 3;24(4):279-95.
  8. https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2019.00350 :
    Firth J, Veronese N, Cotter J, Shivappa N, Hebert JR, Ee C, Smith L, Stubbs B, Sarris J. What is the role of dietary inflammation in severe mental illness? A review of observational and experimental findings. Frontiers in psychiatry. 2019 May 15;10:443755.
  9. https://journals.lww.com/psychosomaticmedicine/fulltext/2019/04000/The_Effects_of_Dietary_Improvement_on_Symptoms_of.7.aspx :
    Firth, J., Marx, W., Dash, S., Carney, R., Teasdale, S.B., Solmi, M., Stubbs, B., Schuch, F.B., Carvalho, A.F., Jacka, F. and Sarris, J., 2019. The effects of dietary improvement on symptoms of depression and anxiety: a meta-analysis of randomized controlled trials. Psychosomatic medicine, 81(3), pp.265-280.
  10. Allot K, McGorry P, Yuen HP, Firth J, et al. (2019). The Vitamins in Psychosis Study: A randomised, double-blind, placebo-controlled trial of the effects of vitamin B12, B6 and folic acid on symptoms and neurocognition in first-episode psychosis. Biological Psychiatry, doi: 10.1016/j.biopsych.2018.12.018
  11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127755/
    Firth J, Stubbs B, Teasdale SB, Ward PB, Veronese N, Shivappa N, Hebert JR, Berk M, Yung AR, Sarris J. Diet as a hot topic in psychiatry: a population‐scale study of nutritional intake and inflammatory potential in severe mental illness. World Psychiatry. 2018 Oct;17(3):365.
  12. Shivappa N, Hébert J, Veronese N, …, Firth J, et al. (2018). The relationship between the dietary inflammatory index and incident depressive symptoms: a longitudinal cohort study. Journal of Affective Disorders, 235: 39-44
  13. https://onlinelibrary.wiley.com/doi/abs/10.1111/eip.12544 :
    Firth J, Rosenbaum S, Ward PB, Curtis J, Teasdale SB, Yung AR, Sarris J. Adjunctive nutrients in first‐episode psychosis: a systematic review of efficacy, tolerability and neurobiological mechanisms. Early intervention in psychiatry. 2018 Oct;12(5):774-83.
  14. Firth J, Stubbs B, Teasdale S, …, Sarris J. (2018). Diet as a hot topic in psychiatry: a population-scale study of nutritional intake and inflammatory potential in severe mental illness. World Psychiatry, 17 (3), 365-367.
  15. https://academic.oup.com/schizophreniabulletin/article-abstract/44/6/1275/4675234 :
    Firth J, Carney R, Stubbs B, Teasdale SB, Vancampfort D, Ward PB, Berk M, Sarris J. Nutritional deficiencies and clinical correlates in first-episode psychosis: a systematic review and meta-analysis. Schizophrenia bulletin. 2018 Oct 17;44(6):1275-92.
  16. https://www.cambridge.org/core/journals/psychological-medicine/article/effects-of-vitamin-and-mineral-supplementation-on-symptoms-of-schizophrenia-a-systematic-review-and-metaanalysis/3CFE6C3B0FED2ED04B9968AD2660EA08  :
    Firth J, Stubbs B, Sarris J, Rosenbaum S, Teasdale S, Berk M, Yung AR. The effects of vitamin and mineral supplementation on symptoms of schizophrenia: a systematic review and meta-analysis. Psychological medicine. 2017 Jul;47(9):1515-27.
  17. Maurizio Pompili, Lucia Longo, Giovanni Dominici, Gianluca Serafini, Dorian A. Lamis, Jerome Sarris, Mario Amore, Paolo Girardi. Polyunsaturated fatty acids and suicide risk in mood disorders: A systematic review. Progress in Neuropsychopharmacology & Biological Psychiatry 2016.
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  18. J. Sarris, J. Murphy, D. Mischoulon, G. I. Papakostas, M. Fava, M. Berk, C. H. Ng. Adjunctive Nutraceuticals for Depression: A Systematic Review and Meta Analyses. Am J Psychiatry 2016, 00(1-13).
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  19. J. Sarris, L. H. Price, L. L. Carpenter, A. R. Tyrka, C. H. Ng, G. I. Papakostas, A. Jaeger, M. Fava, D. Mischoulon. Is S-Adenosyl Methionine (SAMe) for Depression Only Effective in Males? A Re-Analysis of Data from a Randomized Clinical Trial. Pharmacopsychiatry 2015; 48(04/05): 141-144.
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  20. J. Sarris, A. C. Logan, T. N. Akbaraly, G. P. Amminger, V. Balanzá-Martínez, M. P. Freeman, et al (2015). Nutritional medicine as mainstream in psychiatry. Personal View, 2(3): 271-274.
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Hedonia™ is classified as a medical food product. It is specially formulated to address the unique nutritional needs associated with depression. It is recommended that you check with your doctor before taking or adding Hedonia to your daily routine. If you are pregnant, nursing, diagnosed with Bipolar Disorder, and/or taking MAO Inhibitors, you should consult with your doctor first.

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